The zebrafish, also called “Danio rerio” is a tropical freshwater fish known for its usefulness
in scientific research as a vertebrate model organism. It is called zebra
because of five uniform, pigmented, horizontal, blue stripes on the side of the
body, which are reminiscent of a zebra’s stripes.
Zebrafish are
used in lab because they are easy to keep and breed in the lab. They
produce large numbers of fertilized eggs on a regular basis (a single female
can produce up to 500 eggs each week). Their embryos develop rapidly with precursors to all major organs
appearing within 36 hours of fertilization. Its genome is sequenced and easy to
manipulate using reverse genetics tools and insertion of transgenes. What is
also useful about zebrafish is that its chorion, or egg shell, is clear,
which means that developmental processes can be clearly observed under a simple
light microscope. 
Zebrafish have
been used to make several transgenic models of cancer, including melanoma, and
leukemia. They also have been used to model cardiovascular diseases including
heart diseases.
We appreciate the use of model organisms such as zebrafish, yeast and drosophila in medical research and the knowledge that they give to scientist.
Hopefully with
more research and studies, many diseases will be cured.
Mohammed Saleh
Sources: Dr. Craig Albertson slides
-Wikipedia
Sources: Dr. Craig Albertson slides
-Wikipedia
Really liked your blog, zebra fish are so interesting, I remember learning about them in high school. It would have been cool to talk about how zebra fish have been making a significant impact in transgenic models especially different types of cancers.
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