Wednesday, February 26, 2014

MERS Discovery

Middle East Respiratory Syndrome, more commonly abbreviated as MERS is a human disease caused by a type of virus called coronavirus. This disease causes an assortment of respiratory ailments, including shortness of breath, coughing and pneumonia. Along with these symptoms the virus can cause a high grade fever, which to some people can be deadly. About half of the people infected with MERS die from respiratory complications. Although the disease is believed to have originated in the Middle East it is rather widespread, affecting countries such as Saudi Arabia, Qatar, Kuwait, Jordan, United Arab Emirates, Oman, Tunisia, France, Germany, Spain, Italy and Britain. The virus is closely related to SARS, which in the early 2000's caused a deadly outbreak in Asia, infecting thousands and killing hundreds.

Recently, scientists have been able to identify a previously unknown source of this disease, camels. Before this study it had not been known whether humans could contract the disease from animals. This study confirmed that several camels were actively infected with the virus, and that the genetic make up of their version of the virus was very similar, though not identical, to the virus in some infected humans. Maybe even more interestingly though is the fact that only young camels had the actual virus present in their systems. Older camels were much more likely to have antibodies built up against the virus, indicating that the disease is older than previously known.

This study brings up a lot of very relevant questions, one being if the virus has existed in camels for decades why did it take so long to infect humans? The first human cases weren't reported until 2012. The best answer is that the virus hadn't mutated to be able to cross species until recently. Many viruses are specific to their host, which prevents trans-species infections. When a virus develops the ability to cross species it becomes much more dangerous. An example of this we have all heard of is the bird flu. The virus infects birds readily, and jumping from birds to humans cause a world wide health scare recently. So since MERS is a trans species virus should there be a global concern over it? I would say there needs to be more research into the mechanism of transmission of this virus. In some regions which the study observed up to 90% of the camels were or had been infected. These high numbers should be very concerning, and now that his study is available to the public I hope that more awareness is raised. 

Posted by Tim Daly (2)

8 comments:

  1. Viruses are awesome organisms. While its cool too learn about them, it's scary to think how quickly they can adapt and mutate to hurt and possibly kill their hosts. Thanks for the info! Great blog!

    Alex Sroczynkski

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  2. This is definitely a cool article and I thank you for bringing it to our attention. We humans are in a constant "arms race" with viruses and bacteria so its depressing to see normally non-human viruses infect humans. Hopefully one day we can halt the spread of MERS

    Posted by Jacob Geier

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    1. I like that you brought up the term "arms race" Jacob. I think it is important to make a distinction between the biological arms race we have evolved with, and the artificial arms race that as humans we have created. We supply bacteria with the means to become stronger through our over application of antibiotics. We breed viruses that are designed to survive beyond their normal limits.

      Posted by Tim Daly

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  3. Interesting post, it is crazy how once a mutation allows the virus to be transferred among species how quickly it can escalate. I hope more research is done to see how this disease is transmitted and the possible human implications.

    Posted by Morgan Matuszko

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  4. There are many human diseases are related to animals or pets. Knowing that some viruses have the potential to evolve into those can cross species, we should study more on animals and their diseases. Hopefully we can develop treatments those diseases before the viruses be able to cross species.

    Posted by Yim Hui

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    1. I definitely agree with you Yim. Many viruses and other diseases that have caused widespread destruction in humans came from animals. I wonder how much research is really going into animal pathogens. I would assume that there is a lot of research in this area, because of how much we rely on animals, especially as a food source.

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  5. It honestly amazed me the wide-spread abilities viruses have; whether they be teratogens or general trans species viruses, it's unbelievable unnerving, A highly compelling article that makes you wonder what you expose yourself to on a daily basis.
    Nicole Peterkin

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