A new drug, creatively titled AZD05030, has shown to restore synaptic connections as well as memories in mice with Alzheimer's. The drug was originally developed to fight cancer. While it could not fight solid tumor cells, it was able to target plaques that are very common in Alzheimer's. The drug very quickly eliminates many major effects of Alzheimer's, including memory and neuron synapse loss, and the writer's of the original paper are very excited about the progress of their ongoing clinical trials. The Yale science team hopes that soon the drug will be in common clinical circulation soon, helping more people around the world treat their Alzheimer's more effectively than ever thought possible before.
|Glial cells (red) surround alpha beta plaques in mouse cortex with Alzheimer's|
This is a massive scientific breakthrough in the medical world. Alzheimer's has long been deemed untreatable, but the fact that there is a drug out there that can return memory that was lost during the course of the disease is phenomenal. The drug works by stopping one of the steps in the disease's chemical pathway, halting it in it's tracks. This drug also opens up the potential for other drugs that could work against the disease by stopping other steps in it's chemical pathway. This drug is by no means a final cure for Alzheimer's, but it represents a massive step in finding that cure. While AZD05030 is still in clinical trials, things are looking up to potentially find an end-all be-all cure for this disease in the near future!